Paxlovid Tracking Guide 2025: How to Monitor Side Effects, Rebound & Recovery
Updated November 2025 | Free printable tracker + apps to ensure safe COVID treatment
What Is Paxlovid? | Dosage & Timing | Paxlovid Tracking Essentials | Side Effects to Track | Rebound Risk & Monitoring | Drug Interactions | Tracking Tools & Apps | FAQs
What Is Paxlovid? (And Why Track It Closely)
Paxlovid is an oral antiviral for high-risk COVID-19 patients — nirmatrelvir/ritonavir combo. FDA-authorized since 2021, it reduces hospitalization by 89% if started within 5 days of symptoms.[1]
Why track? 5-day course with rebound risk (10–20%), side effects, and 600+ interactions. Proper monitoring prevents ER visits.
Paxlovid Dosage: 5-Day Course Timing
Standard: 300 mg nirmatrelvir + 100 mg ritonavir, twice daily for 5 days. Take with food; space 12 hours apart.
Reduced dose: For kidney impairment (eGFR 30–59): 150/100 mg twice daily.
Paxlovid Tracking: Daily Journal Template
Track to catch issues early. Use this free printable PDF or app.
| Day | Dose Time | Symptoms (1–10) | Vitals (Temp, O2) | Notes (Side Effects?) |
|---|---|---|---|---|
| Day 1 | AM: _____ PM: _____ | Cough: __ Fatigue: __ | Temp: __°F O2: __% | Food taken? Interactions? |
| Day 2 | AM: _____ PM: _____ | Cough: __ Fatigue: __ | Temp: __°F O2: __% | Rebound signs? |
Side Effects to Track Daily
Common (20–30%): altered taste (dysgeusia), diarrhea, hypertension. Rare: Liver issues, rash.
- Track: Blood pressure (ritonavir effect), taste changes, GI symptoms
- Alert: If BP >140/90 or persistent diarrhea → call doctor
Paxlovid Rebound: What to Watch & Track
Rebound: Symptoms return 2–8 days after finishing (10–20% risk, usually mild). Not failure — virus lingers.
Rebound Tracking Tips
- Daily check: Temp, cough, fatigue (scale 1–10)
- Red flags: Fever >100.4°F, O2 <94%, worsening dyspnea → ER
- Duration: Track 14 days post-treatment
Drug Interactions: Track Your Meds
Paxlovid interacts with 600+ drugs (CYP3A inhibitors/inducers). Ritonavir boosts levels.
| Category | Examples | Tracking Action |
|---|---|---|
| Statins | Simvastatin, lovastatin | Pause or adjust; monitor muscle pain |
| Heart Meds | Amiodarone, sildenafil | Monitor BP/heart rate daily |
| Antibiotics | Clarithromycin | Avoid; track for QT prolongation |
Paxlovid Tracking Tools & Apps
- Free PDF Tracker: Download above — printable journal
- Nudge Device: Effortless tracking and reminders
- Apps: Medisafe, MyTherapy (dose reminders + symptom logs)
- Wearables: Fitbit/Apple Watch for O2, HR tracking
Track Paxlovid Effortlessly with Nudge
The Nudge smart pill reminder tracks your 5-day Paxlovid course, logs times effortlessly via device, and alerts for rebound checks. Perfect for high-risk patients. Get Nudge →
Frequently Asked Questions (FAQs)
- Who qualifies for Paxlovid in 2025?
- High-risk adults (age 50+, comorbidities) within 5 days of symptoms. No test required.
- Does Paxlovid prevent long COVID?
- May reduce risk; track symptoms 4+ weeks post-infection.